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Clinical data
Trade namesCytotec, Misodel, other
Pregnancy categoryAU: X (High risk) US: X (Contraindicated) Used for terminating pregnancy
Routes of administrationBy mouth, vaginal, under the tongue
ATC codeA02BB01 ( WHO ) G02AD06 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailabilityextensively absorbed
Protein binding80-90% (active metabolite, misoprostol acid)
MetabolismLiver (extensive to misoprostic acid)
Elimination half-life20–40 minutes
ExcretionUrine (80%)

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    Of patients had pre-induction modified Bishop s score of 3 4, and 3 ― el misoprostol es igual al cytotec. of patients had pre-induction modified Bishop s score of 5.2 The primary measures of safety for the Alfirevic meta-analysis12 were uterine hyperstimulation with FHR changes and cesarean section.

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